| 摘要 |
<p>Pharmaceutical composition comprising R(-)-propylnorapomorphine hydrochloride or S(+)-propylnorapomorphine hydrochloride and/or derivatives thereof, together with antioxidants, solubilizers and permeation activators to facilitate the passage of the active principle through the skin. The pharmaceutical composition is used in matrix (3, 3', 3') of a transdermal patch (1, 1', 1'), for the treatment of disorders of the Central Nervous System and in particular for the treatment of sexual impotence, hemicrania, Parkinson's disease and psychotic disorders. The release of the active principle can be modified by varying the concentrations of the solubilizers or of the permeation activators, or by providing a permeable membrane (4).</p> |
