发明名称 SUPPRESSANT FOR MOLECULAR EXPRESSION FUNCTION
摘要 PROBLEM TO BE SOLVED: To obtain the subject suppressant capable of suppressing or inhibiting functions expressed by a multidimensional structure of a reactional substrate by including a specific 6-membered ring compound containing carbonyl group as an active ingredient. SOLUTION: This suppressant is obtained by including a compound represented by formula I [R1 to R6 are each H, a halogen, a 1-6C alkyl, amidino, a 3-8C cycloalkyl, an aryl or the like; A is H or a group represented by formula II (R7 is a 1-6C alkyl, sulfide or the like; R8 and R9 are each H, allyl or the like)] (e.g. 4-isopropyl-2-cyclohexen-1-one) as an active ingredient. When using the compound as a medicine, the compound can be mixed with a pharmaceutically required ingredient such as a carrier, an excipient or a diluent, prepared as a pharmaceutical composition in a dosage form such as a powder, a granule, a tablet, a capsule or a parenteral injection and administered. The active ingredient is preferably included in an amount of 0.1-80 wt.% in the case of the powder, granule, tablet and capsule and usually preferably 0.01-20 wt.% in the case of the parenteral injection.
申请公布号 JP2000026287(A) 申请公布日期 2000.01.25
申请号 JP19990132913 申请日期 1999.05.13
申请人 KOYAMA SHOZO 发明人 KOYAMA SHOZO;YAMAGUCHI YOSHIHIRO
分类号 C07D295/10;A01N1/02;A01N35/06;A61K31/00;A61K31/12;A61K31/34;A61K31/341;A61K31/343;A61K31/40;A61K31/403;A61K31/404;A61K31/42;A61K31/425;A61K31/426;A61K31/435;A61K31/47;A61K31/495;A61K31/496;A61K31/505;A61K31/535;A61K31/5375;A61K31/5377;A61P7/00;A61P7/02;A61P31/00;A61P31/04;A61P31/12;A61P35/00;A61P37/00;A61P37/06;A61P43/00;C07C49/403;C07C49/463;C07C49/603;C07C49/687;C07C49/713;C07D207/333;C07D209/08;C07D215/14;C07D233/60;C07D239/26;C07D261/08;C07D277/24;C07D307/46;C07D307/80;C07D307/86;C07F9/117 主分类号 C07D295/10
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