| 发明名称 |
RECOMBINANT DNA PRODUCT AND METHODS |
| 摘要 |
An altered antibody is produced by replacing the complementarity determining regions (CDRs) of a variable region of an immunoglobulin (Ig) with the CDRs from an Ig of different specificity, using recombinant DNA techniques. The gene coding sequences for producing the altered antibody may be produced by site-directed mutagenesis using long oligonucleotides.
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| 申请公布号 |
CA1340879(C) |
申请公布日期 |
2000.01.25 |
| 申请号 |
CA19870533071 |
申请日期 |
1987.03.26 |
| 申请人 |
WINTER, GREGORY PAUL WINTER, GREGORY PAUL |
发明人 |
WINTER, GREGORY PAUL WINTER, GREGORY PAUL |
| 分类号 |
C07K14/195;A61K39/395;C07K14/005;C07K16/00;C07K16/46;C07K19/00;C12N5/00;C12N5/10;C12N15/00;C12N15/09;C12P21/00;C12P21/02;C12P21/08;C12R1/91;(IPC1-7):C12N15/13;C07K16/18 |
主分类号 |
C07K14/195 |
| 代理机构 |
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代理人 |
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