PRODUCTION OF 2-CHLORO-5-HYDROXYPYRIDINE

摘要

PROBLEM TO BE SOLVED: To provide a method for simply producing 2-chloro-5-aminopyridine in high yield. SOLUTION: 2-Chloro-5-aminopyridine represented by the following formula (1) is reacted with nitrous acid or a nitrous salt in an aqueous solution of an inorganic acid and the resultant compound is then reacted with water in the presence of a carboxylic acid to produce 2-chloro-5-hydroxypyridine represented by the following formula (2).