Antibody against human interleukin-5-receptor alpha chain

摘要

PCT No. PCT/JP96/02588 Sec. 371 Date May 9, 1997 Sec. 102(e) Date May 9, 1997 PCT Filed Sep. 11, 1996 PCT Pub. No. WO97/10354 PCT Pub. Date Mar. 20, 1997The present invention provides monoclonal antibodies and humanized antibodies which react specifically with a human interleukin-5 receptor alpha chain. The invention also provides hybridomas and transformants which produce the antibodies, the monoclonal antibodies and humanized antibodies, a method for detecting an interleukin-5 receptor alpha chain immunologically by means of these antibodies, as well as a method for diagnosing and treating diseases such as chronic bronchial asthma by means of the monoclonal antibodies and humanized antibodies. The present invention is useful for diagnosis or treatment of diseases such as chronic bronchial asthma.