Nerve growth factor structural analogs and their uses

摘要

PCT No. PCT/CA95/00059 Sec. 371 Date Aug. 7, 1996 Sec. 102(e) Date Aug. 7, 1996 PCT Filed Feb. 7, 1995 PCT Pub. No. WO95/21193 PCT Pub. Date Aug. 10, 1995Cyclic compounds with a 3-dimensional structure that bind at least one neurotrophin receptor (NTR) under physiologic conditions in vitro or in vivo are new. Binding to NTR at least partially mimics or inhibits NT biological activity.