Pharmaceutical dental formulation for topical application of metronidazole benzoate and chlorhexidine gluconate

摘要

A pharmaceutical dental formulation of therapeutically effective amounts of metronidazole benzoate and chlorhexidine gluconate is described. The formulation also includes a gelled hydrophilic and water-dipersible polymer having free carboxylic groups, an aqueous base, a penetration enhancer and a chelating agent. The formulation is for topical application in the form of an aqueous gel in the treatment of periodontal diseases including gingivitis, stomatitis, Apthous ulcers and post-extraction infection.