Using nucleic acids encoding non-toxic mutant SEA and SEB exotoxins from Staphylococcus aureus, compositions and methods for use in inducing an immune response which is protective against staphylococcal aureus intoxication in subjects is described.
申请公布号
WO0002523(A2)
申请公布日期
2000.01.20
申请号
WO1999US15569
申请日期
1999.07.09
申请人
U.S. MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES DEPARTMENT OF THE ARMY;LEE, JOHN, S.;PUSHKO, PETER;SMITH, JONATHAN, F.;ULRICH, ROBERT, G.
发明人
LEE, JOHN, S.;PUSHKO, PETER;SMITH, JONATHAN, F.;ULRICH, ROBERT, G.