| 发明名称 |
PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEINASES |
| 摘要 |
<p>The present invention concerns novel mercaptoalkylpeptidyl compounds of formula (I) which are useful inhibitors of matrix metalloproteinase and/or TNF-mediated diseases including degenerative diseases and certain cancers. The invention also concerns methods of treating patients suffering from disorders or diseases which can be attributed to or are associated with matrix metalloproteinase or TNF activity.</p> |
| 申请公布号 |
EP0728144(B1) |
申请公布日期 |
2000.01.19 |
| 申请号 |
EP19950900237 |
申请日期 |
1994.11.10 |
| 申请人 |
DARWIN DISCOVERY LIMITED |
发明人 |
MONTANA, JOHN;DICKENS, JONATHON;OWEN, DAVID ALAN;BAXTER, ANDREW DOUGLAS |
| 分类号 |
A61K8/00;A61K8/64;A61K38/00;A61P1/02;A61P1/14;A61P7/00;A61P7/02;A61P7/04;A61P9/00;A61P9/10;A61P25/00;A61P29/00;A61P31/00;A61P33/02;A61P35/00;A61P37/00;A61P37/06;A61P43/00;A61Q11/00;C07K5/06;C07K5/062;C07K5/065;(IPC1-7):C07K5/062;A61K38/55 |
主分类号 |
A61K8/00 |
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