| 摘要 |
<p>(A) Cpds. of general formula (I) Z=CH2 or CO R1=H, F, Cl, or Br (B) Salts of I (II). (C) Some cpds. (IV). Analgesics, antiphlogistics, and antipyretics. Dose 50-3000 mg. 4-(p-(1-pyrryl)phenyl)butyronitrile (3.4 g), NaOH (3.3 g), EtOH (30 ml) and H2O (10 ml), were refluxed 18 hr., evapd. in vac., taken up in H2O (30 ml), and extd. with Et2O (70 ml). The H2O phase was sepd., acidified at 0 deg. with c. HCl (7 ml), filtered, washed with ice-water (5 ml), and dried, and the crude product (3.0 g) recryst. from PriOH, giving I, 113-4 deg.</p> |
