| 发明名称 |
ENHANCEMENT OF IMMUNE RESPONSE USING TARGETING MOLECULES |
| 摘要 |
<p>The present invention provides methods of enhancing the immune response to an immunogen and to compositions for use in these methods. In particular the present invention provides a DNA molecule for use in raising an immune response to an antigen. The DNA molecule includes a first sequence encoding a targeting molecule, a second sequence encoding the antigen or an epitope thereof, and optionally a third sequence encoding a polypeptide which promotes dimerization or multimerization of the product encoded by the DNA molecule.</p> |
| 申请公布号 |
EP0972054(A1) |
申请公布日期 |
2000.01.19 |
| 申请号 |
EP19980910530 |
申请日期 |
1998.03.26 |
| 申请人 |
THE COUNCIL OF THE QUEENSLAND;COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION;THE UNIVERSITY OF MELBOURNE;THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH;CSL LIMITED |
发明人 |
BOYLE, JEFFEREY, STEPHEN;BRADY, JAMIE, LOUISE;LEW, ANDREW, MARK |
| 分类号 |
C12N15/09;A61K38/00;A61K39/008;A61K39/015;A61K39/05;A61K39/145;A61K39/385;A61K48/00;A61P31/00;A61P37/04;C07K14/11;C07K14/34;C07K14/435;C07K14/44;C07K14/445;C07K14/47;C07K14/705;C07K16/28;C07K19/00;(IPC1-7):C12N15/62;A61K39/00 |
主分类号 |
C12N15/09 |
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