| 摘要 |
The present invention relates to the use of pyrrolidine and piperidine derivatives of the general formula wherein R1 and R2 are, independently from each other, hydrogen, lower alkoxy, hydroxy, halogen, -CONH2 or -C(O)O-lower alkyl; or taken together are -O-CH2O; R3 and R4 are, independently from each other, hydrogen, lower alkoxy, benzyloxy, halogen, hydroxy, -CONH2 or -SCH3; or taken together are -O-CH2-O-; Y is -CH(OH)-, -(CH2)n-, -C(O)- or -CH(lower alkoxy)-; and m, n and p are 1 or 2; and to their pharmaceutically acceptable addition salts for the treatment of diseases caused by over activation of NMDA receptor subtypes. |
