| 发明名称 |
Protein kinase C inhibitor |
| 摘要 |
This invention provides novel bis-indolylmaleimide macrocycle derivatives of the formula: and solvates thereof. The invention further provides the preparation, pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.
|
| 申请公布号 |
US6015807(A) |
申请公布日期 |
2000.01.18 |
| 申请号 |
US19970966081 |
申请日期 |
1997.11.07 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
ENGEL, GARY LOWELL;FARID, NAGY ALPHONSE;FAUL, MARGARET MARY;JIROUSEK, MICHAEL ROBERT;RICHARDSON, LORI ANN;WINNEROSKI, JR., LEONARD LARRY |
| 分类号 |
A61K31/395;A61K31/40;A61K31/407;A61K31/44;A61P3/08;A61P3/10;A61P43/00;C07D471/04;C07D498/22;(IPC1-7):A01N43/00;A01N55/02;C07D267/22 |
主分类号 |
A61K31/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
