摘要 |
<p>The invention concerns the use of a piperazine derivative of formula (I) wherein: A and B = C=O, C=S or CR7R8 with R7 = H, methyl, cyano, cyanomethyl, CO2CH3 or (C=O)CH3, and R8 = H or phenyl; R1 to R6 = H, OH, or C1-C5 alkoxy; X represents: either C=O, O(C=O), O(C=S), O(SO2), NH(C=O), NH(C=S), NH(SO2), S(C=O) or S(C=S), then Y=NR9R10, CR9R10R11 = H, C1-C5 alkyl, C2-C5 alkenyl or C2-C5 alkynyl or nitrogenous heterocycle comprising 5 to 10 atoms; or O, S, O(C=O)O, NH(C=O)O, or S(C=O)O, then Y = CR9R10R11 with R9, R10, R11 as above; or one of its pharmaceutically acceptable salts for preparing a medicine inhibiting HIV. The invention is useful for treating HIV infection.</p> |