STABILIZED VARIANTS OF STREPTOMYCES SUBTILISIN INHIBITOR

摘要

The present invention relates to variants of Streptomyces subtilisin inhibitor (SSI) and those inhibitors having homology to SSI. Such variants are useful in conjunction with enzymes, particularly proteases, in cleaning compositions and personal care compositions. The variants comprise an amino acid substitution at position 63 corresponding to SSI. Such variants provide greater proteolytic stability in cleaning compositions and personal care compositions. The present invention also relates to cleaning compositions and personal care compositions comprising the present variants, as well as genes encoding the variants.