| 发明名称 |
ANTISENSE OLIGONUCLEOTIDES TARGETED TO IL-15 |
| 摘要 |
The invention features antisense oligonucleotide molecules that specifically bind polynucleotides encoding IL-15. The present invention provides antisense oligonucleotides capable of inhibiting IL-15 expression, and methods of use thereof to reduce activity of IL-15 in tissues in order to treat diseases such as rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis, chronic liver disease, ulcerative colitis and cell proliferative disorders.
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| 申请公布号 |
WO0001851(A1) |
申请公布日期 |
2000.01.13 |
| 申请号 |
WO1999US15499 |
申请日期 |
1999.07.07 |
| 申请人 |
HISAMITSU PHARMACEUTICAL CO., INC.;VEERAPANANE, DANGE;HAMANAKA, SHOJI;HIROYUKI, KUBO;NOZAWA, IWAO |
发明人 |
VEERAPANANE, DANGE;HAMANAKA, SHOJI;HIROYUKI, KUBO;NOZAWA, IWAO |
| 分类号 |
C12N15/09;A61K31/7105;A61K31/711;A61K31/7125;A61K35/76;A61K38/00;A61K47/48;A61K48/00;A61P1/04;A61P1/18;A61P19/02;A61P21/00;A61P25/00;A61P35/00;C07H21/04;C12N15/113;(IPC1-7):C12Q1/68;C12N15/00;C12N15/85;C12N15/86 |
主分类号 |
C12N15/09 |
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