发明名称 |
CHIRAL RECOGNITION POLYMER AND ITS USE TO SEPARATE ENANTIOMERS |
摘要 |
A new polymeric material, a process for forming the material and method of using the material to separate enantiomers of chiral compounds, particularly amino acids and pharmaceuticals are disclosed. A polymeric material can be formed from polyaniline doped with a chiral acid and then extracted with a suitable base. This leaves behind a polymeric material which preferentially traps, and then selectively releases, one enantiomer of a chiral mixture brought in contact with the surface of the polymeric material. In particular, when polyaniline is doped with either R- or S-camphorsulfonic acid (CSA) it takes on a chiral structure. Removing the chiral acid dopant leads to a new chiral polyaniline. The dedoped chiral polyanilines have the ability to discriminate among enantiomers of many compounds which exist in chiral mixtures.
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申请公布号 |
WO0001642(A1) |
申请公布日期 |
2000.01.13 |
申请号 |
WO1999US15083 |
申请日期 |
1999.07.01 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
KANER, RICHARD, B.;KNOBLER, CHARLES, M.;GUO, HAILAN |
分类号 |
C07B57/00;C08G73/02;(IPC1-7):C07B57/00 |
主分类号 |
C07B57/00 |
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