摘要 |
The present invention provides new methods for preparation of various compounds that comprise alicyclic groups with nitrogen or sulfur as ring members, including 2,5-disubstituted tetrahydrothiophenes, 2,5-disubstituted pyrrolidines, 2,6-disubstituted thianes, 2,6-disubstituted hexahydropyridines, 2,7-disubstituted thiepanes, 2,7-disubstituted hexahydroazepines, 2,8-disubstituted thiocanes and 2,8-disubstituted octahydroazocines. The invention further provides novel compounds and pharmaceutical compositions and therapeutic methods that comprise such compounds and compositions.
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申请人 |
LEUKOSITE, INC. |
发明人 |
CHORGHADE, MUKUND, SHANKAR;GURJAR, MUKUND, KESHAO;PALAKODETY, RADHA, KRISHNA;LALITHA, SISTA, VENKATA, SAI;SADALAPURE, KASHINATH;ADHIKARI, SUSANTA, SEKHAR;MURUGAIAH, ANDAPPAN, MURUGAIAH, SUBBAIAH;RAO, BATCHU, VENKATESWARA;TALUKDAR, ARINDAM;TALUKDAR, ARINDAM;ISLAM, AMINUL;HARIPRASAD, CHITTINENI;RAO, ALLA, VENKATA, RANA |