PAROXETINE MALEATE POLYMORPH AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT
摘要
The form B of paroxetine maleate polymorph is characterized by determined data of X ray diffraction: it has a chemical stability which is superior to that of the form A of paroxetine maleate. This superior stability enables to use the new polymorph for the fabrication of medicaments intended to the treatment of troubles related to dysfunctions of the central nervous system. The process for producing the paroxetine maleate comprises the preparation of paroxetine maleate solution and a consequent precipitation.
申请公布号
WO0001693(A1)
申请公布日期
2000.01.13
申请号
WO1999ES00209
申请日期
1999.07.05
申请人
MEDICHEM, S.A.;STAMPA DIEZ DEL CORRAL, ALBERTO;BOSCH LLADO, JORDI;MOLINS GRAU, ELIAS;ONRUBIA MIGUEL, MA DEL CARMEN
发明人
STAMPA DIEZ DEL CORRAL, ALBERTO;BOSCH LLADO, JORDI;MOLINS GRAU, ELIAS;ONRUBIA MIGUEL, MA DEL CARMEN