摘要 |
<p>A slowly rotating separation chamber (12) with an oscillating axial magnetic field gradient created by alternating current solenoid (28a-28d) superimposed on a steady radial gradient in a horizontal chamber is used as part of a flow-through multiunit colloidal magnetic affinity separation device including magnets (30a-30d and 32a-32d). The field-gradient induced microscale particle motion, as well as particle resuspension by chamber rotation, significantly enhances particle-target contact without generating damaging shear forces. Chamber rotation also minimizes sedimentation of non-neutrally buoyant magnetic particles. The alternating current solenoid (28a-28d) are a series of coils arranged along the axial flow direction, a single chamber is utilized as a flow-through multistage separation device, leading to a major increase in volume and reduced 'down' times as compared to batch equipment.</p> |