发明名称 |
Expandable gastroretentive therapeutic system with controlled release of active substance within gastrointestinal tract |
摘要 |
<p>The present invention describes a device for the controlled release of active compounds in the gastrointestinal tract with delayed pyloric passage, having a component expandable on contact with gastric juice, which is surrounded by a polymer covering which is permeable to gastric juice and active compounds. The device contains at least one active compound which is present in a multiparticulate preparation which releases the active compound into the gastric juice with a delay. Compared with conventional pharmaceutical forms with delayed pyloric passage, the release of active compound from a device according to the invention can be better controlled; likewise the device can be easily rolled or folded and can be introduced into capsules without problems.</p> |
申请公布号 |
CZ9902495(A3) |
申请公布日期 |
2000.01.12 |
申请号 |
CZ19990002495 |
申请日期 |
1998.01.09 |
申请人 |
LTS LOHMANN THERAPIE-SYSTEME GMBH |
发明人 |
ASMUSSEN BODO;CREMER KARSTEN;HOFFMANN HANS-RAINER;LUDWIG KARIN;ROREGER MICHAEL |
分类号 |
A61D7/00;A61K9/00;A61K9/48;A61K9/52;A61M31/00;(IPC1-7):A61K9/00 |
主分类号 |
A61D7/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|