| 摘要 |
<p>Compds. useful as antiphologistic, antiallergic, antitussive and analgesic agent are of formula (R1R2)C6H3-X-CH2Y-CH2-R6 (I), where R1 is H, amino alkylamino, alkanoylamino, aroylamino, N-alkyl alkanoylamino, alkylsulphonamido, carbamoyl or ureido, R2 is H, Hal, alkyl or O alkyl, X is O or S, Y = CH2, CHOH alkyl COOCH, alkyl SO2CH. aryl SO2CH or CO, R6 is 3-R4-4R5-4-(R3-C6H4)-piperidino; R3 = halogen, R4 is H, R5 is H or OH or R4 and R5 together is a double bond) and are prepd. by standard methods. Prefd. compds. are 4'- 3- 4-(p-fluorophenyl)-3,6-dihydro-1-(2H)-pyridyl -2-hydroxypr- opoxy -propionanilide-, acetanilide and -isobutyranilide.</p> |
