| 摘要 |
PROBLEM TO BE SOLVED: To obtain a moisture-resistant solid preparation excellent in moistureproofness and handleability under pharmaceutical manufacturing process and excellent in preservability as well, and to provide a method for producing the preparation. SOLUTION: This solid preparation is such one as to comprise a hygroscopic bulk, a coating agent comprising an oil ingredient such as animal/vegetable fat-and-oil, fat and hydrocarbon oil and wax, and a preparation stock. This solid preparation has a relative room temperature moisture absorption of <=65% and relative accelerated moisture absorption of <=80%. The other objective method for producing the above solid preparation comprises heating a mixture of a hygroscopic bulk, a coating agent as mentioned above, a preparation stock, and a solvent followed by molding the mixture and then drying the mixture thus molded. |
