发明名称 |
Smooth muscle mitogen and isolated DNA coding therefor |
摘要 |
A recombinant non-glycosylated mammalian growth factor (BTC-GF) stimulates proliferation of human smooth muscle cells. Especially, the amino acid sequence of the protein deduced from the nucleotide sequence coding for human BTC-GF is as that comprising the amino acids No. 1 to No. 147 of FIG. 10 (SEQ ID NO:18) or the amino acids No. 1 to 80 of FIG. 10, (SEQ ID NO:18) and the amino acid sequence of the protein deduced from the nucleotide sequence coding for mouse BTC-GF is as that comprising the amino acids No. 1 to No. 146 of FIG. 9 (SEQ ID NO:17).
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申请公布号 |
US6013762(A) |
申请公布日期 |
2000.01.11 |
申请号 |
US19980049813 |
申请日期 |
1998.03.27 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD.;CHILDREN'S MEDICAL CENTER CORPORATION |
发明人 |
FOLKMAN, MOSES J.;SHING, YUEN;IGARASHI, KOICHI |
分类号 |
A61K38/00;C07K14/475;(IPC1-7):C07K14/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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