| 摘要 |
PROBLEM TO BE SOLVED: To obtain the subject lysate capable of enhancing the production of IgG antibody, selectively inhibiting the production of IgE antibody and improving atopic or allergic constitution, and useful in foods, etc., by lysing the cell wall of Bacillus bacteria and/or lactic bacteria. SOLUTION: This lysate with immunoregulation activity is obtained by lysing the cell wall of Bacillus bacteria such as Bacillus natto, Bacillus subtilis or Bacillus megaterium and/or lactic bacteria such as Lactobacillus plantarum through the action of a glucosidase-type enzyme such as eggwhite lysozyme and/or endopeptidase-type protease such as bromelain; wherein it is preferable that the cell wall is lysed with a glucosidase-type enzyme in a medium with isotonic pressure, the protoplast thus formed is separated and removed, and the solubilized fraction in the medium is treated with an endopeptidase-type protease. |
