发明名称 |
Pancreas-derived serpin |
摘要 |
The present invention provides nucleotide and amino acid sequences that identify and encode a novel pancreas-derived serpin (PDS) expressed in human pancreas. The present invention also provides for antisense molecules to the nucleotide sequences which encode PDS, expression vectors for the production of purified PDS, antibodies capable of binding specifically to PDS, hybridization probes or oligonucleotides for the detection of PDS-encoding nucleotide sequences, genetically engineered host cells for the expression of PDS, diagnostic tests based on PDS-encoding nucleic acid molecules and a pharmaceutical composition containing PDS capable of binding specifically to a serine protease.
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申请公布号 |
US6013448(A) |
申请公布日期 |
2000.01.11 |
申请号 |
US19970977771 |
申请日期 |
1997.11.25 |
申请人 |
INCYTE PHARMACEUTICALS, INC. |
发明人 |
BRAXTON, SCOTT MICHAEL;WILDE, CRAIG G.;DIEP, DINH |
分类号 |
G01N33/566;A61K31/70;A61K38/00;A61K48/00;A61P1/00;C07K14/81;C07K16/38;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/15;C12Q1/68;G01N33/573;(IPC1-7):C12Q1/68;C07H21/02 |
主分类号 |
G01N33/566 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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