| 摘要 |
The invention presents a biguanide derivative or its salt expressed by a formula: (see formula 1) wherein R represents 3,4-dichlorobenzyl group, 4-chlorophenyl, 3,4-dichlorophenyl group, benzyl group or 4-chlorobenzyl group. wherein R2 represents octyl group, 3,4-dichlorobenzyl group, dodecyl group, decyl group, 3-trifluoromethylphenyl group, 4-bromphenyl group, 4-iodophenyl group, 2,4-dichlorophenyl group, 3,4-dichlorophenyl group, 2,3,4-trichlorophenyl group, 3,4-dimethylphenyl group, 3,4-methylenedioxyphenyl group, 4-t-butylphenyl group 4-ethylthiophenyl group, 1,1,3,3-tetramethylbutyl group, hexyl group, 3-diethylaminopropyl group, (2-diethylamino)-ethyl group, 3-(di-n-butylamino)propyl group, cyclohexylmethyl group, 2,4-dichlorobenzyl group, 4-acetylaminophenyl group, 3,4-methylenedioxybenzyl group, or isobutyl group. (see formula 2) where A represents a lower alkylene group and R3 represents phenyl group which may possess one to three groups selected from a group consisting of halogen atom, lower alkyl group, halogen substituted lower alkyl group and lower alkylthio group as substituent; phenyl lower alkyl group which may posses a halogen atom as substituent on phenyl ring; or alkyl group. This biguanide derivative or its salt is preferably used as the effective amount of a disinfectant for humans, animals, medical appliances, etc.
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