发明名称 |
Compositions and methods for inhibiting bone resorption |
摘要 |
The present invention relates to oral compositions and methods for inhibiting bone resorption in a mammal while counteracting the occurrence of potentially adverse gastrointestinal effects. The compositions useful herein comprise the combination of a pharmaceutically effective amount of a nitrogen-containing bisphosphonate or a pharmaceutically-acceptable salt thereof and a pharmaceutically effective amount of a caspase inhibitor. |
申请公布号 |
AU4702499(A) |
申请公布日期 |
2000.01.10 |
申请号 |
AU19990047024 |
申请日期 |
1999.06.21 |
申请人 |
MERCK & CO., INC. |
发明人 |
ALFRED A. RESZKA |
分类号 |
A61K45/00;A61K31/66;A61K38/00;A61K38/06;A61K38/07;A61K38/55;A61P19/08;A61P19/10;C07K5/08;C07K5/10;C07K5/107;C07K5/113 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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