发明名称 |
THE PREPARATION OF ARYLPHOSPHINES |
摘要 |
A process for preparation of an arylphosphine of the formula R<1>OC-Ar-PR<2>R<3> wherein Ar is aryl or heteroaryl; R<1> is an alkoxy or amine group; and R<2> and R<3> are each any organic group; and each of the respective groups may optionally be substituted with any non-interfering group; comprises the reaction of a sulfonyloxy compound of the formula R<1>OC-Ar-OSO2R<4> wherein R<4> is alkyl, haloalkyl, perhaloalkyl, aryl, aralkyl or alkaryl, with a primary phosphine of the formula HPR<2>R<3>, in a solvent and in the presence of a palladium catalyst and a base. The arylphosphine can then readily be converted to a chiral phosphine ligand.
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申请公布号 |
WO0000498(A1) |
申请公布日期 |
2000.01.06 |
申请号 |
WO1999GB02065 |
申请日期 |
1999.06.30 |
申请人 |
CHIROTECH TECHNOLOGY LIMITED;WINTER, STEPHEN, BENEDICT, DAVID;LENNON, IAN, CAMPBELL |
发明人 |
WINTER, STEPHEN, BENEDICT, DAVID;LENNON, IAN, CAMPBELL |
分类号 |
B01J31/04;C07B61/00;C07F9/50;(IPC1-7):C07F9/50 |
主分类号 |
B01J31/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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