发明名称 |
Hydroxylierte Metaboliten und Derivate von Doxazosin gegen Atherosklerose |
摘要 |
This invention relates to the use of certain hydroxylated metabolites and derivatives of doxazosin and their pharmaceutically acceptable acid addition salts for retarding the development of atherosclerosis in a mammal. Such compounds are useful for reducing atherosclerotic plaque involvement and for retarding and reducing both lipid deposition fibrosis in the development of atherosclerotic plaques. |
申请公布号 |
DE69327128(D1) |
申请公布日期 |
2000.01.05 |
申请号 |
DE1993627128 |
申请日期 |
1993.02.26 |
申请人 |
PFIZER INC., NEW YORK |
发明人 |
WONG, SAMUEL SIU-MING;SWINDELL, ARCHIE CALHOUN |
分类号 |
A61K31/505;A61K31/495;A61P9/10;C07D405/12 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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