发明名称 |
Therapeutic use of bFGF to treat conditions involving adhesion of cytotoxic white cells to endothelium |
摘要 |
A method of treating a condition involving vascular adhesion of cytotoxic white cells by (a) identifying an animal suspected of having a condition involving vascular adhesion of cytotoxic white cells and (b) administering to the animal an amount of bFGF sufficient to decrease cell surface expression of ICAM-I or VCAM-I on endothelial cells, thereby reducing adhesion of cytotoxic white cells to vascular endothelium.
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申请公布号 |
US6010712(A) |
申请公布日期 |
2000.01.04 |
申请号 |
US19970921115 |
申请日期 |
1997.08.29 |
申请人 |
THE GENERAL HOSPITAL CORPORATION;MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
JAIN, RAKESH K.;MELDER, ROBERT J.;KOENIG, GERALD C.;MUNN, LANCE L. |
分类号 |
A61K38/18;A61K48/00;(IPC1-7):A61F2/02 |
主分类号 |
A61K38/18 |
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代理人 |
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主权项 |
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地址 |
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