| 发明名称 |
Trinuclear cationic platinum complexes having antitumor activity and pharmaceutial compositions containing them |
| 摘要 |
PCT No. PCT/EP95/04455 Sec. 371 Date Jul. 25, 1997 Sec. 102(e) Date Jul. 25, 1997 PCT Filed Nov. 13, 1995 PCT Pub. No. WO96/16068 PCT Pub. Date May 30, 1996The present invention relates to trinuclear cationic platinum complexes with alkylene diamine groups connecting the three platinum moieties. The invention also relates to the antitumor activity of these complexes as well as the processes for the preparation thereof and pharmaceutical compositions containing them.
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| 申请公布号 |
US6011166(A) |
申请公布日期 |
2000.01.04 |
| 申请号 |
US19970836667 |
申请日期 |
1997.07.25 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
VALSECCHI, MARIELLA;PAVESI, PAOLO;BUGATTI, CARLO;MENTA, ERNESTO;GIULIANI, FERNANDO;MANZOTTI, CARLA;SPINELLI, SILVANO;FARRELL, NICHOLAS |
| 分类号 |
A61K31/28;A61K31/282;A61P35/00;C07F15/00;(IPC1-7):C07F15/00 |
主分类号 |
A61K31/28 |
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