发明名称 |
Assay systems and methods for measuring P38 map kinase, and modulators thereof |
摘要 |
Assay systems utilizing a reporter construct based on p38 phosphorylation of myocyte enhancer factor 2 (MEF2) transcription factor are provided. The reporter construct and methods of use are provided, as well as methods of treatment of inflammatory and muscular disorders associated with MEF2-regulated gene expression.
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申请公布号 |
US6010856(A) |
申请公布日期 |
2000.01.04 |
申请号 |
US19970922955 |
申请日期 |
1997.09.03 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
ULEVITCH, RICHARD J.;HAN, JIAHUAI;JIANG, YONG;LI, ZHUANG-JEI |
分类号 |
C07K14/47;C12Q1/68;(IPC1-7):C12Q1/68;C12N15/63;C12N1/21;C12N5/10 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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