发明名称 |
Polynucleotides encoding human mitochondrial chaperone proteins |
摘要 |
The present invention provides a human mitochondrial chaperone protein (Hmt-GrpE) and polynucleotides which identify and encode Hmt-GrpE. The invention also provides expression vectors and host cells and a method for producing Hmt-GrpE. The invention also provides for antibodies or antagonists specifically binding Hmt-GrpE, and their use in the prevention and treatment of cancer. The invention also provides diagnostic assays. The invention also provides for the use of Hmt-GrpE in identifying antifungal and antiprotozoal therapeutics.
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申请公布号 |
US6010879(A) |
申请公布日期 |
2000.01.04 |
申请号 |
US19970971158 |
申请日期 |
1997.11.14 |
申请人 |
INCYTE PHARMACEUTICALS, INC. |
发明人 |
BANDMAN, OLGA;GOLI, SURYA K. |
分类号 |
A61K38/00;C07K14/47;C12N5/02;C12N15/12;(IPC1-7):C12P21/06;C12Q1/68;C07H17/00;C07K14/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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