发明名称 Methods for inhibiting uterine fibroid disease
摘要 The present invention provides novel methods of lowering serum cholesterol and inhibiting smoother muscle cell proliferation, particularly restenosis, in humans, and inhibiting uterine fibroid disease and endometriosis in women comprising administering to a human/woman in need of treatment an effective amount of a compound of formula I wherein R is C1-C6 alkyl, C1-C6 alkoxy, halo, or trifluoromethyl; R1 and R2 each are the same or different C1-C6 alkyl group; n is an integer from 2 to 6; and R3 and R4 each are independently C1-C4 alkyl, or combine to form a substituent selected from the group consisting of pyrrolidino, morpholino, piperidino, piperazino, 4-(C1-C6 alkyl)piperazino, and 4-phenyl-piperazino; or a pharmaceutically acceptable salt thereof.
申请公布号 US6011057(A) 申请公布日期 2000.01.04
申请号 US19980109298 申请日期 1998.06.30
申请人 ELI LILLY AND COMPANY 发明人 BRYANT, HENRY U.;DODGE, JEFFREY A.
分类号 C07D311/58;A61K31/35;A61K31/352;A61K31/353;A61K31/4025;A61K31/453;A61K31/496;A61K31/5377;A61P3/06;A61P9/00;A61P13/02;A61P15/00;(IPC1-7):A61K31/55 主分类号 C07D311/58
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