发明名称 |
IMPROVED PROCESSES FOR THE PREPARATION OF D-CHIRO-INOSITOL |
摘要 |
<p>A method for the preparation D-chiro-inositol (I) from kasugamycin (II), comprising the steps of: (a) reacting kasugamycin with an acetylating agent to form a crude hexa-acetate intermediate; (b) purifying the crude intermediate to form purified hexa-acetate intermediate; (c) deacetylating the purified intermediate to form D-chiro-inositol; and (d) isolating the D-chiro-inositol. The method permits efficient, large-scale preparation of D-chiro-inositol without the need for extensive chromatographic purification of the final D-chiro-inositol product.</p> |
申请公布号 |
GR3031009(T3) |
申请公布日期 |
1999.12.31 |
申请号 |
GR19990402087T |
申请日期 |
1999.08.18 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
RILEY, DAVID, A.;BHATIA, ASHOK, V.;CHAMBERLIN, STEVEN, A.;ROBINSON, GREGG, E. |
分类号 |
C07B61/00;C07C27/02;C07C29/09;C07C29/10;C07C29/76;C07C29/80;C07C29/82;C07C29/88;C07C29/94;C07C35/16;C07C67/08;C07C67/62;C07C69/013;C07C69/21;(IPC1-7):C07C29/10 |
主分类号 |
C07B61/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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