发明名称 |
Monoclonal antibodies specific for thrombin hirudin. |
摘要 |
<p>The invention concerns a process for the preparation of hybridoma cells which secrete monoclonal antibodies specific for hirudin, the hybridoma cells themselves, the monoclonal antibodies specific for hirudin secreted by these hybridoma cells, derivatives thereof, and a process for the preparation of said antibodies and derivatives. These monoclonal anti-hirudin antibodies and their derivatives are useful for the determination of hirudin and as an antidote to hirudin. The invention also concerns test kits and pharmaceutical compositions comprising said monoclonal antibodies and/or derivatives.</p> |
申请公布号 |
GR3030993(T3) |
申请公布日期 |
1999.12.31 |
申请号 |
GR19990402071T |
申请日期 |
1999.08.18 |
申请人 |
CIBA-GEIGY AG |
发明人 |
SCHLAEPPI, JEAN-MARC, DR.;BRAUN, DIETMAR G., PROF. DR. |
分类号 |
G01N33/577;A61K31/00;A61K38/00;A61K39/395;A61P7/00;A61P7/02;C07K16/38;C12N5/10;C12N5/20;C12N15/02;C12P21/08;C12R1/91;(IPC1-7):C12N5/20 |
主分类号 |
G01N33/577 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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