发明名称 Derivatives of enantiomerically enriched and substituted thiazolidinodione and pharmaceutical compositions containing them
摘要 The present invention deals with an enantiomerically enriched compound having the formula, I: <IMAGE>, or a tautomeric formula thereof and/or a pharmaceutically acceptable salt thereof and/or a pharmaceutically acceptable solvate thereof, where T represents, for example, a derivative of ethoxyphenyl and T<1> is S; in which more than 50 percent p/p of said compound is present in the form of a compound of formula, IA: <IMAGE>, or a tautomeric formula thereof and/or a pharmaceutically acceptable salt thereof and/or a pharmaceutically acceptable solvate thereof, where T and T<1> are as defined in regard to formula I and the carbon atom ** is an enantiomeric carbon atom. The compounds thus prepared are used in medicine, especially in treatment of hyperglycaemia.
申请公布号 PT102338(A) 申请公布日期 1999.12.31
申请号 PT19990102338 申请日期 1999.07.23
申请人 SMITHKLINE BEECHAM PLC. 发明人 RICHARD MARK HINDLEY;STEFAN ROLAND WORONIECKI
分类号 A61K31/42;A61K31/425;A61K31/426;A61P3/10;C07D263/44;C07D277/24;C07D277/34;C07D413/12;C07D417/12;(IPC1-7):C07D277/24 主分类号 A61K31/42
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