发明名称 3''-DESMETHOXY DERIVATIVES OF ERYTHROMYCIN AND AZITHROMYCIN
摘要 <p>A compound having the formula <IMAGE> (IV) wherein Z is CH2-N(CH3), N(CH3)-CH2, or <IMAGE> R1 and R2 are selected from 1) one of R1 and R2 is OH and the other of R1 and R2 is (C1-C6)alkyl, (C2-C6)alkenyl, or phenyl, with the proviso that Z is not CO; 2) one of R1 and R2 is H and the other of R1 and R2 is NR5R6 wherein R5 and R6 are independently selected from H and (C1-C6)alkyl, or is OR7 wherein R7 is H or (C1-C6)alkyl; and 3) R1 and R2 together form an oxo or oxime group; R3 and R4 are each hydroxyl or together form a carbonate or thiocarbonate group; and pharmaceutically acceptable salts thereof.</p>
申请公布号 GR3031092(T3) 申请公布日期 1999.12.31
申请号 GR19990402175T 申请日期 1999.08.26
申请人 PFIZER INC. 发明人 YANG, BINGWEI, V.
分类号 A61K31/70;A61K31/7042;A61K31/7048;A61K31/7052;A61P31/04;C07H17/00;C07H17/08;(IPC1-7):C07H17/08 主分类号 A61K31/70
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