| 发明名称 |
CYCLIC HYDROXAMIC ACIDS AS METALLOPROTEINASE INHIBITORS |
| 摘要 |
The present application describes novel cyclic hydroxamic acids of formula (I): or pharmaceutically acceptable salt forms thereof, wherein ring B is a 5-7 membered cyclic system containing from 0-2 heteroatoms selected from O, N, NR<a> and S(O)p, and 0-1 carbonyl groups and the other variables are defined in the present specification, which are useful as metalloprotease inhibitors.
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| 申请公布号 |
WO9965867(A1) |
申请公布日期 |
1999.12.23 |
| 申请号 |
WO1999US13723 |
申请日期 |
1999.06.17 |
| 申请人 |
DU PONT PHARMACEUTICALS COMPANY |
发明人 |
XUE, CHU-BAIO;DECICCO, CARL, P.;HE, XIAOHUA |
| 分类号 |
A61K31/167;A61K31/4406;A61K31/4418;A61K31/4427;A61K31/443;A61K31/4433;A61K31/445;A61K31/4465;A61K31/45;A61K31/451;A61K31/4545;A61K31/47;A61K31/4709;A61P1/02;A61P7/02;A61P7/04;A61P9/02;A61P9/04;A61P17/04;A61P17/06;A61P19/02;A61P21/04;A61P25/00;A61P27/02;A61P29/00;A61P31/04;A61P33/06;A61P35/00;A61P35/02;A61P37/06;A61P43/00;C07C259/08;C07D211/16;C07D211/22;C07D211/60;C07D211/76;C07D213/30;C07D213/40;C07D213/61;C07D213/65;C07D215/20;C07D215/22;C07D215/233;C07D401/12;C07D401/14;C07D405/14;C07D409/14;C07D417/14;(IPC1-7):C07C259/08 |
主分类号 |
A61K31/167 |
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