发明名称 TEMPERATURE-SENSITIVE LIPOSOMAL FORMULATION
摘要 Temperature sensitive liposomes containing active agents are described. The liposomes comprise phospholipids and a surface active agent, such as a lysolipid, that increases the amount of active agent released by the liposome at the phase transition temperature of the liposome. Such liposomes are useful in methods of administering active agents using mild hyperthermic conditions.
申请公布号 WO9965466(A1) 申请公布日期 1999.12.23
申请号 WO1999US12964 申请日期 1999.06.09
申请人 DUKE UNIVERSITY 发明人 NEEDHAM, DAVID
分类号 A61K9/127;A61K31/192;A61K31/337;A61K31/437;A61K31/4745;A61K31/517;A61K31/573;A61K31/704;A61K33/24;A61K45/00;A61K47/24;A61K47/34;A61P29/00;A61P31/04;A61P35/00;A61P37/06;(IPC1-7):A61K9/127 主分类号 A61K9/127
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