A novel analogue of insulin has covalently conjugated thereto, preferably at the B1 residue, 3,3',5'-triiodothyroxine. The conjugate is believed to be hepatoselective, whilst it retains insulin receptor binding properties.
申请公布号
WO9965941(A1)
申请公布日期
1999.12.23
申请号
WO1998GB01722
申请日期
1998.06.12
申请人
KINGS COLLEGE LONDON;DEUTSCHES WOLLFORSCHUNGSINSTITUT;JONES, RICHARD, HENRY;BRANDENBURG, DIETRICH;SHOJAEE-MORADI, FARIBA;KLEINJUNG, JENS
