发明名称 THERAPEUTIC COMBINATIONS COMPRISING A SELECTIVE ESTROGEN RECEPTOR MODULATOR AND PARATHYROID HORMONE
摘要 This invention is directed to pharmaceutical combination compositions and methods comprising (-)-cis-6-phenyl-5-(4-(2-pyrrolidin-1-yl-ethoxy)-phenyl)- 5,6,7,8-tetrahydronaphthalene-2-ol or a pharmaceutically acceptable salt thereof and parathyroid hormone or a biologically active fragment thereof, methods of using such compositions and kits containing such compositions. Th e compositions are useful for treating musculoskeletal frailty, including osteoporosis, osteoporotic fracture, low bone mass and frailty.
申请公布号 CA2335078(A1) 申请公布日期 1999.12.23
申请号 CA19992335078 申请日期 1999.05.26
申请人 PFIZER PRODUCTS INC. 发明人 KE, HUA ZHU;THOMPSON, DAVID DUANE
分类号 A61K38/22;A61K;A61K31/40;A61K31/402;A61K31/435;A61K38/29;A61P5/32;A61P19/00;A61P19/08;A61P19/10;C07C;C07D;(IPC1-7):A61K31/40 主分类号 A61K38/22
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