BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (BPI) DELETION ANALOGS

摘要

Novel BPI deletion analogs are provided that consist of amino acid residues (10 through 193) of mature human BPI wherein the cysteine residue at BPI amino acid position (132) is replaced by another amino acid. Fusion proteins comprising these analogs are also provided, as are polynucleotides encoding these products, materials and methods for their recombinant production, compositions and medicaments of these products, and therapeutic uses for these products.