发明名称 INHIBITORS OF SEROTONIN REUPTAKE
摘要 A compound of Formula (I) where A-B is -C=CH- or -CHCH2-; n is 0 or 1; R1 is H or C1-C4 alkyl; R2 is H, methyl, or ethyl and Aryl is naphthyl or heteroaryl , each optionally monosubstituted with a substituent selected from the group consisting of H, halo, hydroxy, C1-C4 alkyl, C1-C4 alkoxy, cyano, nitro, carboaxamido, and trifluoromethyl; or pharmaceutically acceptable salts or hydrates thereof, provided that when n is 1, A-B is -CHCH2-, and a method fo r the inhibition of serotonin reuptake in mammals.
申请公布号 CA2335322(A1) 申请公布日期 1999.12.23
申请号 CA19992335322 申请日期 1999.06.04
申请人 ELI LILLY AND COMPANY 发明人 ROCCO, VINCENT PATRICK;KOCH, DANIEL JAMES
分类号 A61K31/4409;A61K31/4427;A61K31/443;A61K31/445;A61K31/4465;A61K31/451;A61K31/4525;A61K31/454;A61K31/4709;A61K31/4725;A61P3/04;A61P15/10;A61P25/00;A61P25/06;A61P25/14;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P25/34;A61P43/00;C07D211/12;C07D211/16;C07D211/20;C07D211/22;C07D211/60;C07D211/70;C07D211/74;C07D401/04;C07D401/06;C07D405/04;C07D405/06;C07D413/04;C07D413/06;C07D417/04;C07D417/06;(IPC1-7):A61K31/435;C07D217/00;C07D215/02;C07D215/04;C07D411/04;C07D211/06;C07D411/06;A61K31/47 主分类号 A61K31/4409
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