发明名称 METHODS OF ADMINISTERING CAMPTOTHECIN COMPOUNDS FOR THE TREATMENT OF CANCER WITH REDUCED SIDE EFFECTS
摘要 Methods of administering camptothecin compounds such as irinotecan hydrochloride to reduce a diarrhea side effect and methods of treating cancer and AIDs with camptothecin compounds including administering the camptothecin compounds while maintaining the intestinal lumen and the bile at an alkaline pH.
申请公布号 CA2300892(A1) 申请公布日期 1999.12.23
申请号 CA19992300892 申请日期 1999.06.18
申请人 THE GEORGE WASHINGTON UNIVERSITY 发明人 BOUSCAREL, BERNARD;KOBAYASHI, KUNIHIKO
分类号 C07D491/22;A61K9/00;A61K9/107;A61K31/4745;A61K31/565;A61K31/575;A61K33/00;A61K33/10;A61K47/02;A61K47/12;A61P35/00;A61P35/02;A61P43/00;(IPC1-7):A61K31/47;A61K31/35;A61K31/40;A61K31/405 主分类号 C07D491/22
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