| 发明名称 |
MONOCLONAL ANTIBODIES THAT RECOGNIZE ANTIGENS ASSOCIATED WITH TUMOR METASTASIS |
| 摘要 |
This invention provides tumor metastasis-inhibiting monoclonal antibodies, mAb 41-2, mAb 50-6 and mAb 1A-5. The antigen recognized by mAb 50-6 and mAb 1A-5 has been identified as the PETA-3 antigen. The antigen recognized by mAb 41-2 has been identified as a novel tumor metastasis-associated antigen. Compositions and methods are provided that are useful for treating and diagnosing metastatic tumors.
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| 申请公布号 |
WO9966027(A1) |
申请公布日期 |
1999.12.23 |
| 申请号 |
WO1999US13480 |
申请日期 |
1999.06.15 |
| 申请人 |
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK |
发明人 |
TESTA, JACQUELINE, E.;QUIGLEY, JAMES, P.;SEANDEL, MARCO |
| 分类号 |
A61K38/00;C07K14/47;C07K14/705;C07K16/18;C07K16/28;(IPC1-7):C12N5/12;C07K16/30;A61K39/395;C12N15/11 |
主分类号 |
A61K38/00 |
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