| 发明名称 |
PYRROLO[2,3-d]PYRIMIDINE COMPOUNDS |
| 摘要 |
<p>A compound of formula (I) wherein R<1>, R<2> and R<3> are as defined in the formula which are inhibitors of the enzyme protein tyrosine kinases such as Janus Kinase 3 and as such are useful therapy as immunosuppresive agents for organ transplants, lupus, multiple sclesoris, rheumatoid arthritis, psoriasis, Type I diabetes and complications from diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, Crohn's disease, Alzheimer's disease, Leukemia and other autoimmune diseases.</p> |
| 申请公布号 |
WO9965909(A1) |
申请公布日期 |
1999.12.23 |
| 申请号 |
WO1999IB01110 |
申请日期 |
1999.06.14 |
| 申请人 |
PFIZER PRODUCTS INC.;BLUMENKOPF, TODD, ANDREW;FLANAGAN, MARK, EDWARD;BROWN, MATTHEW, FRANK;CHANGELIAN, PAUL, STEVEN |
发明人 |
BLUMENKOPF, TODD, ANDREW;FLANAGAN, MARK, EDWARD;BROWN, MATTHEW, FRANK;CHANGELIAN, PAUL, STEVEN |
| 分类号 |
A61K31/505;A61K31/519;A61K31/5377;A61K31/55;A61P1/04;A61P3/10;A61P5/14;A61P11/06;A61P17/04;A61P19/02;A61P25/00;A61P25/28;A61P29/00;A61P35/00;A61P35/02;A61P37/06;C07D487/04;C07D519/00;(IPC1-7):C07D487/04 |
主分类号 |
A61K31/505 |
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