A method of preparing a composition of a reagent, which method comprises the steps of (i) forming empty liposomes; (ii) mixing the liposomes from step (i) with a sugar solution and a reagent; and (iii) drying the mixture from step (ii). The compositions will generally comprise less than 10 % w/v sucrose. The method can be used to form small liposomes with high entrapment efficiency. It is particularly useful in the production of pharmaceuticals.
申请公布号
WO9965465(A1)
申请公布日期
1999.12.23
申请号
WO1999GB01911
申请日期
1999.06.16
申请人
THE SECRETARY OF STATE FOR DEFENCE;GREGORIADIS, GREGORY;ZADI, BRAHIM;JAYASEKERA, PRAMUKH, NALAKA