| 摘要 |
The new cpds are of formula: in which R is H or alkyl, R1 is alkyl, phenyl or phenyl alkylene, R2 is H or alkyl, R3 and R4 are H, alkyl, phenylalkylene, dialkylamino-alkylene or R5, R6-phenyl where R5 and R6 are H, alkyl, CF3 or COOH, or NR3R4 represents R7, R8-pyrrolidino, R7, R8 pyridazinyl R7, R8-piperidino, R7, R8-pyrazolyl, R7, R8-pyrimidyl R7, R8 dihydropyridazinyl or R7, R8-piperazinyl, where R7 and R8 are H, alkyl or hydeozyalkyl, (all alkyl gps being lower alkyl) together with their acid addn salts. They are prepared by reaction of the corres. 4-alkoxy, or 4-halo-cpds with HNR3R4. They have CNS depressant antiinflammatory and analgesic activity, and may be used in the treatment of asthma. |
